Inter must balance the Scudetto race with the Champions League Final, so Lautaro Martinez should be rested against Lazio, though several top players are ready to start.
Inter must balance rest with strong XI

According to Sky Sport Italia and FCInterNews, Henrikh Mkhitaryan, Davide Frattesi and Benjamin Pavard will all be available against Lazio, even if they probably won’t be in the starting XI.
Lautaro Martinez is still working separately to regain full fitness after a muscle scare in the first leg of the semi-final against Barcelona, so at most he’ll be risked for the final day of the season against Como.
The aim remains to have him at his best for the Champions League Final with Paris Saint-Germain on May 31.

Sky Sport Italia report that we could see a lot less squad rotation for them in the Lazio match, so bringing back the likes of Marcus Thuram, Francesco Acerbi, Nicolò Barella, Federico Dimarco, Hakan Calhanoglu and goalkeeper Yann Sommer to the starting XI.
While Inter are hosting Lazio, Napoli face a very tricky trip to Cristian Chivu’s Parma.